Higher total physical activity was associated with increased heart rate variability (partial regression coefficient 0.05 for log-RMSSD, P=0.019), which was not modified by insulin resistance.
Cross-Sectional (n=2,016)
Does physical activity improve heart rate variability and is this association modified by insulin resistance in adults aged 30-79 years?
Higher physical activity is associated with improved parasympathetic modulation (higher HRV and lower HR), an effect that is independent of insulin resistance.
Effect estimate: Partial regression coefficient 0.05 for log-RMSSD; 1.86 for pNN50
p-value: p=0.019 for log-RMSSD; 0.001 for pNN50
BACKGROUND: Autonomic activity is possibly influenced by physical activity (PA). However, it remains unclear whether this association is modified by insulin resistance. METHODS: This population-based study between 2009 and 2012 included 2016 men and women aged 30-79 years. The PA was assessed using a validated questionnaire based on sleep, occupation, transportation, household characteristics, and leisure-time PA. Heart rate (HR) and heart rate variability (HRV) in the sitting position were determined from 5-minute recordings of pulse waves detected by a fingertip sensor. The HRV was calculated as frequency (standard deviation of normal-to-normal NN intervals SDNN), root mean square of successive differences (RMSSD), and percentage differences between normal NN intervals >50 milliseconds pNN50) and time domains. Insulin resistance was evaluated using the homeostasis model assessment index (HOMA-IR). RESULTS: HR, RMSSD, and pNN50 were related to the total and moderate/vigorous PA tertiles in models that included HOMA-IR. The partial regression coefficient of total PA per 1-SD increase was .05 (P = .019) for log-transformed RMSSD and 1.86 (P = .001) for pNN50. No interactive associations were observed between PA and HOMA-IR. CONCLUSIONS: Low total PA was associated with increased HR and low levels of RMSSD and pNN50, reflecting parasympathetic modulation that was not modified by insulin resistance.
Saito et al. (Fri,) reported a cross-sectional. Physical activity was evaluated on Heart rate and heart rate variability (SDNN, RMSSD, pNN50) (Partial regression coefficient 0.05 for log-RMSSD; 1.86 for pNN50, p=0.019 for log-RMSSD; 0.001 for pNN50). Higher total physical activity was associated with increased heart rate variability (partial regression coefficient 0.05 for log-RMSSD, P=0.019), which was not modified by insulin resistance.
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