What question did this study set out to answer?

The aim is to evaluate the administration of IMIG for measles prophylaxis in infants post-exposure.

May 16, 2026

Intramuscular Immunoglobulin for Measles Postexposure Prophylaxis

Key Points

The aim is to evaluate the administration of IMIG for measles prophylaxis in infants post-exposure.
IMIG was administered at a dose of 0.5 ml/kg to infants after probable measles exposure.
Coordination with local health department and health care facilities for effective administration planning.
A plan for IMIG administration was developed and utilized for follow-up exposure events.
Establishment of a comprehensive IMIG administration plan for multiple settings in Utah.
Improved guidelines for dosing and administration following exposure events were suggested.
Facilitation of timely prophylaxis in infants after measles exposure.

Abstract

AbstractIntramuscular immunoglobulin (IMIG) administered at a dose of 0.5 ml/kg is an option for prophylaxis in infants after exposure to measles. The weight-based dosing volumes require multiple or large-volume injections; however, no clear administration guidelines exist. In 2025, the Utah Department of Health and Human Services (DHHS) assisted with coordination of IMIG administration after an exposure event at a pediatric clinic. Utah DHHS worked with the local health department and health care facility to develop a plan for administration that has been used in subsequent exposure events in Utah.

Intramuscular Immunoglobulin for Measles Postexposure Prophylaxis

Key Points

Abstract

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