Depressed heart failure patients were 2.3 times more likely to self-report poor medication adherence than nondepressed patients (p=0.006), though objectively measured adherence did not differ.
Observational (n=244)
Is depression associated with worse medication adherence in adults with Stage C heart failure?
In patients with Stage C heart failure, depression is associated with worse self-reported medication adherence but not worse objectively measured adherence, suggesting depressed patients may overestimate their nonadherence.
Effect estimate: OR 2.3
p-value: p=0.006
The purpose of the study was to explore the association between depression and medication adherence in heart failure (HF) patients. Studies have shown that people with depression are likely to be nonadherent to their prescribed medication treatment. But other studies suggest that nonadherence may be overestimated by people with depression. A total of 244 adults with Stage C HF completed the study. Self-reported medication adherence was obtained using the Basel Assessment of Adherence Scale (BAAS); objective data on medication adherence were collected using the electronic Medication Event Monitoring System (MEMS). Depression was measured via self-report with the Patient Health Questionnaire (PHQ-9). There was a significant difference between depressed and nondepressed participants in self-reported medication nonadherence (p = .008), but not in objectively measured medication nonadherence (p = .72). The depressed sample was 2.3 times more likely to self-report poor medication adherence than those who were nondepressed (p = .006).
Tang et al. (Tue,) conducted a observational in Stage C heart failure (n=244). Depression vs. Nondepressed participants was evaluated on Self-reported and objectively measured medication adherence (OR 2.3, p=0.006). Depressed heart failure patients were 2.3 times more likely to self-report poor medication adherence than nondepressed patients (p=0.006), though objectively measured adherence did not differ.