Key result
Depressed heart failure patients were 2.3 times more likely to self-report poor medication adherence than nondepressed patients (p=0.006), though objectively measured adherence did not differ.
Why the study?
Is depression associated with worse medication adherence in adults with Stage C heart failure?
Population
244 adults with Stage C heart failure
Comparison
Depression vs No depression (nondepressed participants)
Design
Cross-sectional
Authors
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Depressed HF patients may overestimate nonadherence via self-report; leaves open whether depression impairs objective adherence or warrants targeted screening.
Observational (n=244)
Is depression associated with worse medication adherence in adults with Stage C heart failure?
Effect estimate: OR 2.3
p-value: p=0.006
In patients with Stage C heart failure, depression is associated with worse self-reported medication adherence but not worse objectively measured adherence, suggesting depressed patients may overestimate their nonadherence.
Tang et al. (2013) conducted an observational in Stage C heart failure (n=244). Depression vs. Nondepressed participants was evaluated on Self-reported and objectively measured medication adherence (OR 2.3, p=0.006). Depressed heart failure patients were 2.3 times more likely to self-report poor medication adherence than nondepressed patients (p=0.006), though objectively measured adherence did not differ.
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