The advent of Quality 5.0, characterized by human-centricity, sustainability, and resilience, necessitates a reimagining of traditional Lean Six Sigma (LSS) methodologies. This paper synthesizes 150 seminal works to propose a transformative framework integrating LSS with emerging technologies (AI, IoT, digital twins) and socio-technical systems. A systematic literature review and conceptual analysis identifies ten key techniques that align LSS with Quality 5.0, emphasizing collaborative human-AI workflows, real-time analytics, and sustainable value streams. Case studies from manufacturing, healthcare, and services illustrate the framework's efficacy, while challenges like data security and workforce upskilling are critically examined. The study contributes a roadmap for organizations to navigate the Quality 5.0 transition, balancing technological agility with human empowerment.
Roy et al. (Wed,) studied this question.