Highly Regioselective Butylation of N‐Sulfonyl‐1,2,3‐triazoles by the Formation of Quaternary Carbon‐Centered C(sp3)─N Bonds

Key Points

• The reaction achieves good yields of 71%–83%, highlighting its efficiency in forming C(sp3)─N bonds.
• The method utilizes tert-butyl hydroperoxide for butylation, indicating it can proceed without additional catalysts.
• This process involves a radical addition to triazoles, followed by an aromatic desulfonation step, showcasing its uniqueness.
• The regioselectivity observed in the butylation of triazoles paves the way for new synthetic applications in organic chemistry.