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September 19, 2025Russian Ophthalmological Journal0 citationsOpen Access

Tear Composition Changes in Retinal Disorders

Changes of tear metabolism in retinal pathology

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Authors

НЧН. Б. ЧесноковаВНВ. В. НероевТПТ. А. Павленко

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Overview

This review highlights changes in tear composition related to diabetic retinopathy and macular degeneration, indicating potential for early diagnostics.

Key Points

  • Tear metabolism reflects local eye physiological changes, with relevant metabolites linked to retinal disease progression.
  • A correlation was found between specific tear metabolites and the stage of retinal pathology, unlike blood concentrations.
  • The analysis of tear fluid can serve as a non-invasive method for investigating retinal conditions and monitoring disease.
  • The emerging technologies in tear fluid analysis may facilitate its integration as a liquid biopsy in clinical settings.
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Чеснокова et al. (2025) studied this question.

synapsesocial.com/papers/68d464f831b076d99fa646f8https://doi.org/10.21516/2072-0076-2025-18-3-158-165
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