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October 3, 2025Journal of Health Population and NutritionOpen Access

Effects of ketogenic diet on muscle mass, strength, aerobic metabolic capacity, and endurance in adults: a systematic review and meta-analysis

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Authors

YWYaqi WangQXQingzhong XiaoZZZhenming Zhang

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Overview

Systematic review finds no significant muscle mass loss in adults on ketogenic diet, suggesting potential benefits for aerobic metabolic capacity.

Key Points

  • No significant differences were found in muscle mass or strength between ketogenic diet and other diets.
  • The ketogenic diet led to a significant decrease in fat-free mass and fat mass compared to control groups.
  • Improvements in fat oxidation were observed during exercise testing while muscle performance metrics remained stable.
  • Further randomized controlled trials are needed to confirm the effects of ketogenic diets on muscle parameters.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68dfe93cdaa1363beb049e64https://doi.org/10.1186/s41043-025-01090-z
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The effect of ketogenic diets on metabolic parameters among obese diabetic adults: Systematic review and meta-analysis2026
  2. 2Effects of ketogenic diet on obesity indices, lipid profile, and glycemic control parameters in athletes: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials2026
  3. 3Ketogenic diets and cardiovascular health balancing metabolic benefits against lipid-related risk2026
  4. 4Effects of Low-Carbohydrate and Ketogenic Diets on Anaerobic Performance in Competitive Athletes: A Systematic Review and Meta-Analysis2026
  5. 5Sparing Muscle While Losing Fat: A Narrative Review of Ketogenic Diets and Lean Mass Preservation During Weight Loss2026