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August 27, 2024Open Access

Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity

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CLChen‐Yi LiaoJHJasmijn H.M. HundscheidJCJustin Crawford

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Liao et al. (2024) studied this question.

synapsesocial.com/papers/68e5ac88b6db643587545fbdhttps://doi.org/10.1101/2024.08.26.609699
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity2025
  2. 2Abstract 737: Arrays of 3D ECM-embedded fibroblast clusters for characterization of ECM remodeling by primary cancer associated fibroblasts and for evaluation of drugs attenuating fibrotic ECM remodeling2024
  3. 3O146: Investigating the cell-matrix interplay in fibrotic remodelling using renal 3D <i>in vitro</i> models2024
  4. 4Fibrotic Extracellular Matrix Preferentially Induces a Partial Epithelial-Mesenchymal Transition Phenotype in a 3-D Agent Based Model of Fibrosis2024
  5. 5BPS2026 – Scaffold-dependent matrix remodeling function of dermal fibroblasts2026