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August 14, 2024Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition0 citations

High-Resolution Myelin Water Imaging Using MPnRAGE

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JWJ. A. WeaverSKSteven KecskemetiJGJosé Guerrero‐Gonzalez

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Abstract

A T1-only method to extract a quantitative myelin water fraction, utilizing a 3D radial k-space MPnRAGE sequence that reconstructs hundreds of different inversion time (TI) images in the same scan used for high-resolution T1-weighted morphometry was developed. To address high sensitivities to additive image noise of this complex model, a multi-pass fitting algorithm was prototyped that provides educated initial guesses and constraints on the underlying parameters.

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Weaver et al. (2024) studied this question.

synapsesocial.com/papers/68e5c52db6db64358755bc5ehttps://doi.org/10.58530/2023/3307
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Myelin water imaging from an 8 minute scan at 64mT via image reconstruction and multicomponent T2 fitting in a low-rank space2025
  2. 2Cartesian MPnRAGE for Efficient Simultaneous Multi‐Contrast and Quantitative Relaxometry Imaging2026
  3. 3Cartesian MPnRAGE for Efficient Simultaneous Multi-Contrast and Quantitative Relaxometry Imaging2025
  4. 4On the feasibility of myelin water imaging at low-field MRI using multi-echo GRASE2025
  5. 5Mesoscale Myelin Water Fraction Mapping at 3T with Self-navigated Motion Correction2025