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August 9, 2024Open Access

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

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Authors

KJK. Lakshmi JayarajRKRitesh KumarSSSukanya Shyamasundar

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Cite This Study

Jayaraj et al. (2024) studied this question.

synapsesocial.com/papers/68e5cdc0b6db64358756483ehttps://doi.org/10.1101/2024.08.08.607139
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Integrating Machine Learning and Single-Cell Sequencing: Decoding Histone Deacetylase Genes-Based Diagnostic Features and Immune Cell Dynamics in Ischemic Stroke2025
  2. 2Arresting the bad seed: HDAC3 regulates proliferation of different microglia after ischemic stroke2024 · 54 citations
  3. 3Epigenetic Regulation in Ischemic Neuroprotection: The Dual Role of HDACs and HATs in Neuroinflammation and Recovery2025 · 11 citations
  4. 4The Molecular Mechanisms of HDACi in Regulating Ischemic Stroke2026
  5. 5SELECTIVE INHIBITION OF HDAC6 MODULATES MICROGLIAL POLARIZATION AND ATTENUATES NEUROINFLAMMATION IN AN LPS-INDUCED NEURODEGENERATIVE MOUSE MODEL2026