0885 Exploring Sleep Health in the Context of COPD and Obesity: Insights from a Population-Based Cross-Sectional Study

Abstract Introduction Many individuals with obstructive lung disease such as COPD suffer from sleep disturbances. Poor sleep quality is related to disease severity. COPD has been associated with obesity in a bidirectional manner, though few studies have examined the interaction between COPD, obesity, and aspects of sleep health including quality and duration. This study aims to examine if decreased sleep duration and trouble sleeping are associated with increased risk of COPD and obesity. Methods Using data from three consecutive rounds of the National Health and Nutrition Examination Survey (2013-14, 2015-16, and 2017-18), a cross-sectional analysis was conducted. Sleep quality was assessed through the survey by inquiring if subjects experienced trouble sleeping. Sleep duration was categorized into normal (7-8 hours of sleep), short ( 7 hours of sleep), and long (8 hours of sleep). Weight was categorized into normal weight, overweight, obese, and severely obese. Poisson regression and multinomial logistic regression analyses were used. Adjusted incidence rate ratio (aIRR) and adjusted relative Risk Ratios (aRRR) with their 95% CI were reported. Results The total sample size was 16,939, with females comprising the majority (52%), and ages ranging from 20 to 80 years. Those with COPD were more likely to report trouble sleeping (aIRR 1.48, p 0.001). Obese and severely obese groups were also associated with trouble sleeping (aIRR 1.27 and 1.50 respectively, p 0.001). An increased likelihood of trouble sleeping (p 0.001) was observed among individuals with COPD and overweight (aIRR 1.54), obesity (aIRR 1.89), and severe obesity (aIRR 1.97). COPD was also found independently associated with long sleep duration (IRR 1.50, p 0.004); however, in the same model, severely obese groups were significantly associated with shorter sleep duration (aRRR: 1.39, p: 0.002). Conclusion In the current study, COPD was associated with long sleep duration and trouble sleeping. Increasing obesity was associated with short sleep duration and trouble sleeping, consistent with previous findings that sleep deprivation likely contributes to obesity. Support (if any)