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March 15, 2024Circulation64 citations

Small Extracellular Vesicles From Infarcted and Failing Heart Accelerate Tumor Growth

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TCTal CallerIRItai RotemOSOlga Shaihov–Teper

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Abstract

Myocardial infarction (MI) and heart failure are associated with an increased incidence of cancer. However, the mechanism is complex and unclear. Here, we aimed to test our hypothesis that cardiac small extracellular vesicles (sEVs), particularly cardiac mesenchymal stromal cell-derived sEVs (cMSC-sEVs), contribute to the link between post-MI left ventricular dysfunction (LVD) and cancer.

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Caller et al. (2024) studied this question.

synapsesocial.com/papers/68e73cb2b6db6435876b5f48https://doi.org/10.1161/circulationaha.123.066911
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