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Small Extracellular Vesicles From Infarcted and Failing Heart Accelerate Tumor Growth | Synapse

March 15, 2024Circulation64 citations

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Small Extracellular Vesicles From Infarcted and Failing Heart Accelerate Tumor Growth

TCTal CallerCardio-Oncology IRItai RotemHebrew University of Jerusalem OSOlga Shaihov–TeperTel Aviv University

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Resumen

Myocardial infarction (MI) and heart failure are associated with an increased incidence of cancer. However, the mechanism is complex and unclear. Here, we aimed to test our hypothesis that cardiac small extracellular vesicles (sEVs), particularly cardiac mesenchymal stromal cell-derived sEVs (cMSC-sEVs), contribute to the link between post-MI left ventricular dysfunction (LVD) and cancer.

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Cite This Study

Caller et al. (Fri,) studied this question.

synapsesocial.com/papers/68e73cb2b6db6435876b5f48 https://doi.org/https://doi.org/10.1161/circulationaha.123.066911