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July 1, 2024Journal of NanobiotechnologyOpen Access

Cardiac-derived extracellular vesicles improve mitochondrial function to protect the heart against ischemia/reperfusion injury by delivering ATP5a1

Xuan Liu Qingshu Meng Shanshan Shi Xuedi Geng Enhao Wang Yinzhen Li Fang Lin Xiaoting Liang Xiaoling Xi Wei Han Huimin Fan Xiaohui Zhou

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Abstract

Numerous studies have confirmed the involvement of extracellular vesicles (EVs) in various physiological processes, including cellular death and tissue damage. Recently, we reported that EVs derived from ischemia-reperfusion heart exacerbate cardiac injury. However, the role of EVs from healthy heart tissue (heart-derived EVs, or cEVs) on myocardial ischemia-reperfusion (MI/R) injury remains unclear.

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Cite This Study

Liu et al. (2024) studied this question.

synapsesocial.com/papers/68e61ca0b6db6435875aef2a https://doi.org/10.1186/s12951-024-02618-x

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