November 30, 2025Organic Chemistry Frontiers2 citations

DBU-Promoted 4+3 Annulation of Pyrrole-2-carbaldehyde Derivatives with Indene-2carbaldehydes: Synthesis of Indene-Fused Pyrrolo1,2-aazepines

LCLi Jia Chen YHYong-Yu He YWYu Qing Wang

Key Points

Indene-fused pyrrolo[1,2-a]azepines were synthesized successfully using the developed method.
The reaction demonstrated a broad substrate scope and proceeded under mild conditions.
This strategy utilizes base-promoted [4+3] annulation for effective synthesis of complex compounds.
Results highlight the potential for further applications in organic synthesis.

Abstract

A base-promoted 4+3 annulation of pyrrole-2-carbaldehydes with indene-2-carbaldehydes for synthesizing indene-fused pyrrolo1,2-aazepines has been developed. The reaction proceeds under mild conditions and demonstrates a remarkably broad substrate scope, accommodating a...

Ask AI

Helpful

Bookmark

View Full Paper

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/692b94261d383f2b2a37838b https://doi.org/10.1039/d5qo01433f

Ask AI

Helpful

Bookmark

View Full Paper

November 30, 2025Organic Chemistry Frontiers2 citations

DBU-Promoted 4+3 Annulation of Pyrrole-2-carbaldehyde Derivatives with Indene-2carbaldehydes: Synthesis of Indene-Fused Pyrrolo1,2-aazepines

View Full Paper

LCLi Jia Chen YHYong-Yu He YWYu Qing Wang

Key Points

Indene-fused pyrrolo[1,2-a]azepines were synthesized successfully using the developed method.
The reaction demonstrated a broad substrate scope and proceeded under mild conditions.
This strategy utilizes base-promoted [4+3] annulation for effective synthesis of complex compounds.
Results highlight the potential for further applications in organic synthesis.

Abstract

Ask AI

Helpful

Bookmark

View Full Paper

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/692b94261d383f2b2a37838b https://doi.org/10.1039/d5qo01433f

Ask AI

Helpful

Bookmark

View Full Paper