Single-cell transcriptomic profiling reveals aberrant CD4⁺ naive T cell differentiation driving immune activation in Behçet’s uveitis

Key Points

• Dysregulated T cell differentiation drives immune activation in Behçet’s uveitis, leading to inflammation.
• Key insights suggest a coordinated immune response influencing ocular inflammation.
• Assessment utilizing single-cell transcriptomic profiling highlights critical pathways in immune modulation.
• These findings emphasize potential therapeutic targets for managing immune dysregulation and preventing damage.