In patients with CBL-related STEMI, PKP significantly reduced main vessel-TLR (0% vs 30%, P = .001) and main vessel-TVMI (0% vs 20%, P = .014) compared to PSP.
Does POT-kissing-POT compared to POT-side-POT reduce MACE in STEMI patients with culprit coronary bifurcation lesions following provisional stenting?
In STEMI patients with bifurcation lesions undergoing provisional stenting, PKP and PSP techniques resulted in comparable mid-term MACE rates, though PKP showed lower main vessel TLR and TVMI in left main bifurcations.
Absolute Event Rate: 0% vs 0%
The present study retrospectively assessed clinical outcomes of proximal optimization technique (POT)-kissing-POT (PKP) and POT-side-POT (PSP) in ST-segment elevation myocardial infarction (STEMI) patients with culprit coronary bifurcation lesion (CBL) following a provisional stenting (PS). This large-scale multicenter (n = 10) study included STEMI patients with culprit CBLs who underwent PKP or PSP following PS. The primary endpoint was defined as the major adverse cardiac events (MACE; cardiac death, target vessel myocardial infarction TVMI, or clinically driven target lesion revascularization TLR). Consecutive patients (n = 596; male: 491 82.3%, mean age: 58.1 ± 11.7 years) were included. The study cohort was divided into 2 groups: PKP (n = 386) and PSP (n = 210). In the overall population, mid-term MACE (hazard ratio HR: 0.921, P = .461) did not differ in individuals with CBL-related STEMI treated with either PKP or PSP. The frequency of main vessel-TLR (0% vs 30%, P = .001) and main vessel-TVMI (0% vs 20%, P = .014) were significantly lower in the PKP group in the left main bifurcation localization. Diabetes mellitus (HR: 2.628, P < .001), high SYNTAX score (HR: 1.081, P < .001), and bifurcation localization (HR: 2.109, P = .014) were found to be independent predictors of MACE. In the overall population, risk-adjusted MACE rates for culprit CBLs were comparable between both techniques.
Akman et al. (Sat,) reported a other. In patients with CBL-related STEMI, PKP significantly reduced main vessel-TLR (0% vs 30%, P = .001) and main vessel-TVMI (0% vs 20%, P = .014) compared to PSP.