What question did this study set out to answer?

This case report explores the relationship between platelet gene resistance and acute thrombosis after percutaneous coronary intervention (PCI).

January 10, 2026International Journal of Emergency Medicine0 citationsOpen Access

A case report: reflections on the formation of acute thrombotic events after PCI in patients with acute ST-Segment elevation myocardial infarction

JYJiaqiang YangHuaihua University JYJiaru YangNantong University HHHaigang HuangHuaihua University

Key Result

Acute thrombosis occurred within 30 minutes after emergency coronary stent implantation in a 57-year-old male with ST-segment elevation myocardial infarction.

Key Points

This case report explores the relationship between platelet gene resistance and acute thrombosis after percutaneous coronary intervention (PCI).
Presentation of a classic case of acute thrombosis after stent implantation.
Patient diagnosed with acute ST-segment elevation myocardial infarction.
Examination of diagnostic and therapeutic strategies employed.
Acute in-stent thrombosis occurred within 30 minutes of stent implantation.
The patient experienced significant chest pain prior to diagnosis.

Structured PICO

Population

1 57-year-old Han Chinese male presenting with acute ST-segment elevation myocardial infarction (STEMI).

Intervention

Emergency percutaneous coronary intervention (PCI) with a 3.5 × 24 mm everolimus-eluting stent, followed by repeat PCI with intracoronary prourokinase and tirofiban for acute in-stent thrombosis, and switching from clopidogrel to ticagrelor based on genetic testing.

This case highlights the importance of considering clopidogrel resistance and utilizing genetic testing in patients who develop acute in-stent thrombosis after PCI for STEMI.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Platelet gene resistance may result in acute thrombosis, although clinical reports are scarce.This article presents a classic case of acute in-stent thrombosis and discusses its diagnostic and therapeutic strategies.The patient, a 57-year-old male, was admitted due to chest pain that lasted for one hour. After a thorough examination, he was diagnosed with acute ST-segment elevation myocardial infarction. Acute thrombosis rapidly occurred within 30 minutes following emergency coronary stent implantation.

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