Higher moderate-to-vigorous physical activity (MVPA) was associated with a 17% lower risk of cardiac conduction disease (HR 0.83), while increased sedentary behavior raised the risk by 5% (HR 1.05).
Does higher moderate-to-vigorous physical activity and lower sedentary behavior reduce the risk of incident cardiac conduction disease in adults?
Objective accelerometer data demonstrates that substituting sedentary time with moderate-to-vigorous physical activity is associated with a significantly lower risk of developing cardiac conduction disease.
Absolute Event Rate: 0% vs 0%
Daily activity has a distinct hierarchy of movement behaviors. The association between 24-hour movement behaviors and cardiac conduction disease (CCD) remains unclear. We aimed to investigate the association between accelerometer-measured 24-hour movement behaviors and CCD risk. A total of 92,436 UK Biobank participants who wore wrist accelerometers for 7 consecutive days were included, with a median follow-up of 6.1 years. Multivariable Cox proportional hazards models were used to investigate the associations between 24-hour movement behaviors (sleep, sedentary behavior, light-intensity physical activity LIPA, and moderate-to-vigorous intensity physical activity MVPA) and the risk of CCD. Compositional data analysis was performed to estimate the effects of reallocating time among 24-hour movement behaviors. Among the 92,436 participants (median age 58 years; interquartile range, 50–63; 54% female), 1,442 developed incident CCD (2.58 per 1,000 person-years) during the follow-up. Greater sedentary behavior was associated with an increased risk of CCD (hazard ration HR, 1.05; 95% confidence interval CI, 1.02–1.08), whereas higher MVPA was associated with a lower risk (HR, 0.83; 95% CI, 0.75–0.92). Sleep duration and LIPA were not significantly associated with CCD risk. Reallocating 30 min/day to MVPA from other movement behaviors was associated with a 4% lower risk of CCD (HR, 0.96; 95% CI, 0.93–0.98). Conversely, reallocating 30 minutes/day to sedentary behavior was associated with a 3% increased risk (HR, 1.03; 95% CI, 1.01–1.05). Similar patterns were observed for specific CCD outcomes, including second- or third-degree atrioventricular block and pacemaker implantation. Higher volumes of MVPA were associated with a lower risk of CCD, whereas increased sedentary behavior was associated with higher risk, highlighting the importance of preventive activity patterns.
Kim et al. (Sun,) reported a other. Higher moderate-to-vigorous physical activity (MVPA) was associated with a 17% lower risk of cardiac conduction disease (HR 0.83), while increased sedentary behavior raised the risk by 5% (HR 1.05).