January 10, 2026Clinical Medicine Research0 citationsOpen Access

Patterns of Drug Therapy Among Diabetic Hypertensive Patients - A Single Center Study in Bangladesh

JLJahanara LaizuDhaka Medical College and Hospital KGKinkar GhoshDhaka Shishu Hospital ASAl Reza Md SayeedUniversity of Southern Denmark

Key Result

Among diabetic hypertensive patients, 49% received mono antihypertensive therapy, highlighting a reliance on single-drug approaches for treatment.

Key Points

The study aims to evaluate the patterns of drug therapy among diabetic hypertensive patients in a medical center in Bangladesh.
Conducted a retrospective analysis of 78 diabetic hypertensive patients
Included those receiving at least one anti-diabetic and one anti-hypertensive drug
Data was processed using MS Excel and SPSS version 23.0
Analyzed male-female ratio, age, BMI, and drug therapy patterns
49% used mono antihypertensive therapy, 36% used dual therapy, and 15% used triple therapy
The majority of diabetic hypertensive patients received mono anti-diabetic therapy
Insurance or treatment costs for insulin users were higher compared to those on other treatments

Structured PICO

Population

78 diabetic hypertensive patients treated at a single center in Bangladesh, mean age 53.2 years, 56% male. Inclusion criteria: received at least one anti-diabetic and one anti-hypertensive drug.

Outcome

Patterns of drug therapy (proportion of patients on mono, dual, or triple therapy for hypertension and diabetes)

In a single-center Bangladeshi cohort, the majority of diabetic hypertensive patients were managed with monotherapy for both hypertension and diabetes, indicating potential underutilization of combination therapies.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Hypertension is extremely prevalent in patients with diabetes. Limited data exist on whether patterns of drug therapy among diabetic hypertensive patients are consistent with evidence-based practice guidelines. There are many variations in prescribing patterns of diabetic hypertensive patients needs much care while choosing drugs. We have very limited research-based information regarding the patterns of drug therapy among diabetic hypertensive patients. The aim of this study was to assess the patterns of drug therapy among diabetic hypertensive patients. This retrospective study was conducted in the Department of Pharmacology, Uttara Adhunik Medical College and Hospital, Dhaka, Bangladesh during the period from January 2000 to December 2020. In total 78 diabetic hypertensive patients treated in the mentioned hospital were enrolled in this study as study subjects. As per the inclusion criteria of this study, only those patients who got at least one anti-diabetic and one anti-hypertensive drug in treatment were included. Proper written consents were taken from all the participants before data collection. All data were processed, analyzed and disseminated by using MS Excel and SPSS version 23.0 program as per necessity. In this study, the male-female ratio of the participants was 1.3:1. The mean ±SD age (Year) and BMI (Body Mass Index) (Kg/msup2/sup) of our participants were 53.2 ±6.82 and 32.41 ±2.49 respectively. For our patients, 87% and 13% drugs were used through oral and parenteral routes respectively. In this study, among all of our participants, as antihypertensive drug therapy, in 49%, 36% and 15% cases mono, duel and triple antihypertensive drugs were used respectively. In this study, among all of our participants, as anti-diabetic drug therapy, in majority of the patients, mono-therapy was used whereas, in 24% cases double and in 10% cases triple drug therapy was used. Majority of the diabetic hypertensive patients are treated by mono antihypertensive and mono antidiabetic therapy. The treatment cost of insulin receiving patients are higher than that of other diabetic hypertensive patients.

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