Recombinant Lactobacillus reuteri: A Novel Probiotic Strategy for Controlling Helicobacter pylori Infection

Key Points

• The research aims to explore the effectiveness of recombinant Lactobacillus reuteri in managing Helicobacter pylori infections.
• Conducted 16S rRNA gene sequencing to analyze gut microbiota changes
• Administered recombinant Lactobacillus reuteri to a murine model
• Characterized the intestinal microbiota composition pre- and post-treatment
• Significant alterations in intestinal microbiota were observed post-treatment
• Indications of reduced Helicobacter pylori levels in treated mice