ABSTRACT We report the study of the two enantiomers of the water‐soluble cryptophane 1 by Synchrotron Radiation Circular Dichroism (SRCD) in DMSO, LiOH/H 2 O, NaOH/H 2 O, KOH/H 2 O, and CsOH/H 2 O solutions. Interestingly, SRCD gives access to new Cotton bands that could not be detected with a conventional CD spectrometer. Our findings reveal that the low‐lying excited states detected by SRCD spectroscopy are extremely sensitive to the concentration of the basic solution. In contrast, except for the thallium cation, the nature of the cationic species has only a little impact on the overall shape of the SRCD spectra in LiOH/H 2 O (0.1 M) solution.
Brotin et al. (Thu,) studied this question.