The Resting Full-cycle Ratio (RFR) is diagnostically equivalent to iFR and better detects significant coronary stenoses throughout the entire cardiac cycle.
Does Resting Full-cycle Ratio (RFR) provide diagnostic equivalence to iFR in detecting physiologically significant coronary stenoses?
RFR is a valid non-hyperemic index that is diagnostically equivalent to iFR but evaluates the full cardiac cycle, potentially identifying significant stenoses missed by segment-specific assessments.
RFR is diagnostically equivalent to iFR but unbiased in its ability to detect the lowest Pd/Pa during the full cardiac cycle, potentially unmasking physiologically significant coronary stenoses that would be missed by assessment dedicated to specific segments of the cardiac cycle.
Svanerud et al. (2018) studied this question. The Resting Full-cycle Ratio (RFR) is diagnostically equivalent to iFR and better detects significant coronary stenoses throughout the entire cardiac cycle.