A 3D model to evaluate cell chemotaxis within a heterogenic tumor microenvironment

Key Points

• The aim is to evaluate how cells migrate within a complex tumor microenvironment using a 3D model.
• Developed a 3D tumor model to replicate cell interactions.
• Assessed cell chemotaxis in different tumor conditions.
• Analyzed the effects of heterogeneity on cell movement.
• Observed distinct patterns of cell migration in response to varying microenvironmental factors.
• Identified key interactions that influence tumor progression within the 3D model.