PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
January 22, 2026Organic & Biomolecular Chemistry0 citations

Remote-stereocontrolled (3+2)-annulation of pyrrolidinone-based MBH carbonates with 2-arylideneindane-1,3-diones

View Full Paper
RLRongzhen LiCZChangzhen ZhaiXCXuling Chen

Key Points

  • The aim is to explore a new enantioselective annulation method using MBH carbonates and arylideneindane diones.
  • Utilized a chiral phosphine catalyst
  • Conducted remote-controlled reactions
  • Performed under mild conditions
  • Successfully achieved enantioselective (3+2)-annulation
  • Constructed complex molecules efficiently

Abstract

With the assistance of a chiral phosphine catalyst, a remote-controlled enantioselective (3+2)-annulation between pyrrolidinone-based Morita-Baylis-Hillman (MBH) carbonates and 2-arylideneindane-1,3-diones has been successfully realized under mild conditions. This reaction efficiently constructs...

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/6971bdcf642b1836717e2740https://doi.org/10.1039/d5ob01719j
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1PPh <sub>3</sub> -Promoted Remote ε′,ε′-Regioselective (4 + 1) Annulation of Pyrrolidinone-Based MBH Carbonates with 1-Heterodienes to Access Highly Substituted 1,6-Diazaspiro[4.4]nonenes2026 · 2 citations
  2. 2Regioselective and Diastereoselective (5+1)‐Annulations: Access to Functionalized Hexahydroisoindoles from Morita–Baylis–Hillman Carbonates and 3‐Aryl‐3‐Oxopropanenitriles2026
  3. 3Phosphine-catalyzed sequential [4+ ]/[2+3] annulation of <i>o</i> -amino arylaldimines with Morita–Baylis–Hillman (MBH) carbonates2026
  4. 4Lewis Base Controlled (4 + 3) and (4 + 2) Annulations of MBH Carbonates with Benzofuran‐derived Azadienes: Access to Highly Substituted Benzofuro[3,2‐b]azepines and Spirotetrahydroquinolines2024 · 5 citations
  5. 5Chiral Phosphine Ligands of COAP and SKP Switched Regiodivergent Asymmetric Allylic Alkylation of MBH Adducts2024 · 1 citations