Abstract The human prostate develops from the urogenital sinus through epithelial bud formation and branching, however the spatial dynamics of progenitor populations during these early stages remain poorly characterized. To addresses this gap, we used a human fetal prostate at 14 weeks of gestation for serial sectioning, yielding approximately 200 sections of 10 µm thickness. Six sections were profiled using spatial transcriptomics with the Visium HD platform, while the remaining sections were H 2026 Jan 20-22; Philadelphia PA. Philadelphia (PA): AACR; Cancer Res 2026;86 (2Suppl): Abstract nr B059.
Emmanouela Perisynaki (Tue,) studied this question.