What question did this study set out to answer?

The research aims to examine the effectiveness of bioceramic paste and diode laser application in pulp therapy and their influence on dentin sialoprotein expression.

January 22, 2026Restorative Dentistry & Endodontics0 citationsOpen Access

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Effect of combined application of premixed bioceramic paste and diode laser in vital pulp therapy: an immunohistochemical randomized controlled split-mouth in vivo animal experiment

MSMo’men A. Salama DFDalia M. Fayyad MRMohamed Rabie

Key Points

The research aims to examine the effectiveness of bioceramic paste and diode laser application in pulp therapy and their influence on dentin sialoprotein expression.
Randomized controlled split-mouth design
In vivo animal model
Application of premixed bioceramic paste and diode laser
Immunohistochemical analysis to assess DSP expression
Bioceramic paste showed similar effectiveness to MTA in promoting DSP expression.
Diode laser application did not influence DSP expression in this model.

Abstract

Well-Root PT demonstrated comparable efficacy to MTA in promoting DSP expression, supporting its use as an effective direct pulp capping material. Diode laser application prior to capping had no effect on DSP expression in this experimental model.

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Effect of combined application of premixed bioceramic paste and diode laser in vital pulp therapy: an immunohistochemical randomized controlled split-mouth in vivo animal experiment

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Abstract

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