What question did this study set out to answer?

This research aims to identify factors correlated with endomysial fibrosis in anti-SRP-IMNM.

January 23, 2026Clinical and Experimental Rheumatology0 citations

Factors associated with endomysial fibrosis in anti-signal recognition particle antibody immune-mediated necrotising myopathy

JYJiaqi Yuan MYMengTing Yang YZYiming Zheng

Key Points

This research aims to identify factors correlated with endomysial fibrosis in anti-SRP-IMNM.
Analyzed MRI findings related to fatty infiltration
Examined the relationship between fibrosis and immunotherapy resistance
Endomysial fibrosis is linked to the presence of fatty infiltration on MRI
Resistance to immunotherapy may be associated with fibrosis development

Abstract

In anti-SRP-IMNM, endomysial fibrosis may be the pathological basis of fatty infiltration observed on MRI and may be associated with resistance to immunotherapy.

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