Background and Objectives Plantar warts, caused by the human papillomavirus (HPV), are common skin growths that predominantly affect children and adolescents. These warts can lead to discomfort and have a significant impact on quality of life. This study aims to assess the effectiveness and safety of microneedling with bleomycin for plantar warts. Our goal is to determine whether this innovative approach can provide better relief for patients suffering from these persistent lesions. Patients and Methods The assessment of treatment efficacy involved measuring the size of warts and conducting photographic comparisons to evaluate healing status. Secondary outcomes included the monitoring of recurrence rates and the treatment‐related adverse effects. Results 45 patients aged 10–24 years, with a total of 360 warts treated, primarily with bleomycin in Group A, where 80% of patients achieved a full response. Analysis showed that lesion diameter influenced treatment outcomes, with lesions measuring 1 cm or less showing significantly better responses ( p = 0.04). Conclusion The combination of topical bleomycin and microneedling is a promising and safe treatment for plantar warts, although variability in study outcomes necessitates further research with larger samples and longer follow‐up to assess long‐term efficacy and safety.
Dayeh et al. (Thu,) studied this question.