To assess the efficacy and safety of statin therapy in older individuals.
Conducted an individual participant data meta-analysis pooling data across 28 randomized controlled trials.
Evaluated individual participant outcomes across randomized trials to determine the therapeutic impact of statins in older age groups.
Assessed the cardiovascular benefits and potential safety concerns associated with statin treatment in older adults.
Abstract
Australian National Health and Medical Research Council, National Institute for Health Research Oxford Biomedical Research Centre, UK Medical Research Council, and British Heart Foundation.