Primary endpoints in randomized controlled trials for older adults with cancer: A scoping review

Key Points

• This review seeks to identify the endpoints commonly used in randomized controlled trials involving older adults with cancer.
• Conducted a scoping review of existing literature.
• Evaluated endpoints featured in randomized controlled trials for older adults.
• Analyzed the consistency of incorporating patient-relevant outcomes.
• Confirmed that survival is the main endpoint in trials.
• Found that patient-relevant outcomes are often inconsistently included.
• Highlighted the need for more patient-centered trial designs.