Correction: Barszczewska-Pietraszek et al. Polθ Inhibitor (ART558) Demonstrates a Synthetic Lethal Effect with PARP and RAD52 Inhibitors in Glioblastoma Cells. Int. J. Mol. Sci. 2024, 25, 9134

Key Points

• This research aims to explore the interaction between the polθ inhibitor ART558 and PARP/RAD52 inhibitors in glioblastoma cells.
• Conducted in vitro experiments with glioblastoma cell lines.
• Assessed the effects of ART558 in combination with PARP and RAD52 inhibitors.
• Analyzed cell viability and apoptosis to determine the synthetic lethal effect.
• ART558 significantly reduced cell viability when combined with PARP and RAD52 inhibitors.
• The combination treatment led to increased apoptosis in glioblastoma cells.
• Findings support the potential for using polθ inhibitors in glioblastoma therapy alongside other inhibitors.