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February 2, 2026Biomaterials Science4 citations

ROS-Responsive Antioxidant Hydrogel with Immunomodulatory Activity for Promoting Diabetic Wound Healing

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YLYurao LiuQYQianqian YangLZLing Zhang

Key Points

  • The aim is to develop a ROS-responsive hydrogel that reduces oxidative stress to improve healing in diabetic wounds.
  • Developed a ROS-responsive antioxidant hydrogel.
  • Evaluated the hydrogel's effects on oxidative stress in wound healing models.
  • Assessed the immunomodulatory activity of the hydrogel.
  • The hydrogel significantly reduced oxidative stress in diabetic wounds.
  • Improved wound healing rates were observed compared to controls.
  • Enhanced immunomodulatory responses were identified with the hydrogel application.

Abstract

The accumulation of reactive oxygen species (ROS) in the microenvironment of diabetic wounds can trigger oxidative stress and hinder wound healing. This study developed a novel ROS-responsive antioxidant hydrogel relying...

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6980fdc7c1c9540dea80f895https://doi.org/10.1039/d6bm00018e
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