Amlodipine Suppresses Lung Metastasis by Increasing Cell Stiffness

Key Points

• The aim is to investigate how amlodipine affects tumor cell stiffness and its impact on lung metastasis.
• Evaluated the effects of amlodipine on tumor cell properties in vitro.
• Measured cell stiffness using appropriate mechanical assessments.
• Assessed lung metastasis in relevant experimental models.
• Amlodipine treatment significantly increased tumor cell stiffness.
• Lung metastasis was significantly reduced following treatment with amlodipine.