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February 2, 2026The Analyst0 citations

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An oxidative cleavage-based HCR-CRISPR/Cas12a biosensor for highly sensitive detection of hypochlorous acid

XLXia LiuGeneral Cardiology XWXiangyue WangMinjiang University SHShaoying HeMinjiang University

Key Points

The aim is to develop a highly sensitive biosensor for detecting hypochlorous acid using oxidative cleavage and CRISPR/Cas12a technology.
Constructed an oxidative cleavage-based HCR-CRISPR/Cas12a biosensor
Focused on hypochlorous acid detection
Achieved highly sensitive detection of hypochlorous acid
Demonstrated effectiveness of biosensor compared to traditional methods

Abstract

An oxidative cleavage-based HCR-CRISPR/Cas12a biosensor was constructed for HClO detection.

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Cite This Study

Liu et al. (Thu,) studied this question.

synapsesocial.com/papers/6980fecbc1c9540dea811385 https://doi.org/https://doi.org/10.1039/d5an01299f

基于氧化裂解的HCR-CRISPR/Cas12a生物传感器用于高度灵敏的次氯酸检测 | Synapse