Regioselective electrochemical 7-endo-dig selenocyclization of N-benzyl propiolamides to access selenated benzocazepinones

Key Points

• To develop an electrochemical method for the regioselective selenocyclization of N-benzyl propiolamides.
• Utilized electrochemical selenocyclization technique
• Focused on N-benzyl propiolamides and diselenides
• Avoided the use of metal reagents or oxidants
• Achieved excellent functional group tolerance
• Demonstrated regioselectivity in selenocyclization reactions
• Accessed selenated benzo[c]azepinones effectively