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Understand the rising burden of herpes zoster in Chinese adults and its implications for healthcare management.

February 8, 2026Infectious Diseases and Therapy1 citationsOpen Access

Rising Burden of Herpes Zoster among General Adults and Increased-Risk Groups in Eastern China, 2015–2021: A Population-Based Cohort Study

ZLZhenwei LiZhejiang Chinese Medical University SGShenjia GuZhejiang Chinese Medical University JLJiajun LiZhejiang Chinese Medical University

Key Points

Understand the rising burden of herpes zoster in Chinese adults and its implications for healthcare management.
Population-based cohort study
Data collection from adults in Eastern China from 2015 to 2021
Focus on age and risk groups
Analysis of healthcare resource use and costs
Increased burden of herpes zoster observed among adults in Eastern China
Postherpetic neuralgia identified as the main cost driver
Recommendations made for prioritizing zoster vaccination for adults aged 50 and over

Abstract

HZ imposes a rising, age- and risk-concentrated burden in Chinese adults, with PHN being the principal driver of resource use and costs. These real-world estimates support prioritising zoster vaccination for adults ≥ 50 years and clinically vulnerable groups, and integrating HZ surveillance and management within chronic-disease programmes.

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