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February 8, 20260 citations

Therapeutic potential of polyphenols in managing thalassemia: A comprehensive review.

SJSajjad Jamali BJBehzad Jamali MGMarjan Golabi

Key Points

This review explores the therapeutic potential of polyphenols in managing thalassemia, focusing on iron chelation.
Comprehensive review of literature on polyphenols and flavonoids
Examination of their iron-chelating properties
Evaluation of side effects in thalassemia management
Polyphenols demonstrate significant iron-chelating capacity
May cause fewer side effects compared to traditional treatments
Promising therapeutic options for thalassemia management

Abstract

The iron-chelating capacity of polyphenols and flavonoids which may have fewer side effects in patients with thalassemia, has garnered significant attention and holds a promise for therapeutic purposes.

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Therapeutic potential of polyphenols in managing thalassemia: A comprehensive review. | Synapse

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Jamali et al. (Thu,) studied this question.

synapsesocial.com/papers/698827f00fc35cd7a8846fc5 https://doi.org/https://doi.org/10.22038/ajp.2025.26013