Special Issue “Invasion and Metastasis in Brain Cancer”

Key Points

• To explore the biological mechanisms behind invasion and metastasis in brain tumors, particularly gliomas and metastatic tumors.
• Review of literature on gliomas and metastases from various systemic malignancies.
• Analysis of biological features that enable infiltration into the brain parenchyma.
• Discussion of the unique microenvironment of the central nervous system.
• Identified common biological characteristics facilitating tumor invasion in brain tissue.
• Noted adaptations of tumors to the distinct microenvironment of the central nervous system.
• Highlighted implications for treatment strategies for brain cancer.