Imiquimod is a low molecular weight compound acting as a local immune response modifier and activating factors of both inborn and acquired immunity (especially T-helpers 1), causing antiviral, antitumor and immunoregulatory effects. It stimulates TLR-7/8 receptors, triggering the immune response mechanisms. It is used in dermatology for the treatment of diseases caused by human papillomavirus and has various antiproliferative and immunomodulatory effects. It is also used for reproduction of the mouse models of psoriasis.
SOROKINA et al. (Tue,) studied this question.