What question did this study set out to answer?

The study aims to evaluate the biological activities of Ganoderma lucidum extract and its suitability as a cosmetic ingredient.

Cosmetic potential of Ganoderma lucidum (Reishi) extract in a topical cream formulation

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Investigates Ganoderma lucidum extract's biological activities in a topical cream, suggesting its potential for cosmetic use.

The study aims to evaluate the biological activities of Ganoderma lucidum extract and its suitability as a cosmetic ingredient.
Measured antioxidant capacity using a copper(II)‐based assay.
Assessed tyrosinase inhibition with human melanoma cells.
Tested cytotoxicity in human keratinocyte cells using the AlamarBlue® method.
Developed a topical cream through a multi‐phase emulsification technique and characterized its properties.
Conducted microbiological safety and preservative efficacy assessments according to regulations.
Reishi extract achieved 861 μmol TE/g in antioxidant activity and 30% tyrosinase inhibition.
Demonstrated a broader safety margin compared to argireline peptide and α‐arbutin, which were more cytotoxic.
The cream maintained a stable pH and viscosity without phase separation or integrity loss.
Microbiological analysis showed counts below regulatory limits, with effective preservative efficacy.

Küçük et al. (2026) studied this question.

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View Full Paper

Ask AI

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Authors

Investigates Ganoderma lucidum extract's biological activities in a topical cream, suggesting its potential for cosmetic use.

The study aims to evaluate the biological activities of Ganoderma lucidum extract and its suitability as a cosmetic ingredient.
Measured antioxidant capacity using a copper(II)‐based assay.
Assessed tyrosinase inhibition with human melanoma cells.
Tested cytotoxicity in human keratinocyte cells using the AlamarBlue® method.
Developed a topical cream through a multi‐phase emulsification technique and characterized its properties.
Conducted microbiological safety and preservative efficacy assessments according to regulations.
Reishi extract achieved 861 μmol TE/g in antioxidant activity and 30% tyrosinase inhibition.
Demonstrated a broader safety margin compared to argireline peptide and α‐arbutin, which were more cytotoxic.
The cream maintained a stable pH and viscosity without phase separation or integrity loss.
Microbiological analysis showed counts below regulatory limits, with effective preservative efficacy.

Küçük et al. (2026) studied this question.

View Full Paper

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