Evaluation of the protective effects of selenium against iron overload–induced toxicity in rats using a multiple-markers approach

Key Points

• The study aims to evaluate how selenium can protect against toxicity caused by excess iron in the body.
• Evaluated selenium's effects on rats with iron overload
• Assessed oxidative stress levels and organ damage
• Used multiple biomarkers to measure outcomes
• Selenium reduced oxidative stress markers
• Decreased organ damage was observed
• Improvements in iron metabolism were noted