What question did this study set out to answer?

Evaluate the prognostic significance of CCDC18-AS1 in gastric cancer and understand its role in tumor progression.

February 12, 2026Biomarkers in Medicine0 citations

Prognostic value of CCDC18-AS1 in gastric cancer and its regulatory effect on tumor progression

LLLei LiBGI Group (China)LYLi YangXuzhou Medical College PXPei Xinrong

Key Points

Evaluate the prognostic significance of CCDC18-AS1 in gastric cancer and understand its role in tumor progression.
Analysis of CCDC18-AS1 expression levels in gastric cancer samples
Assessment of prognosis correlation with CCDC18-AS1 levels
Investigation of CCDC18-AS1's interaction with miR-214-3p
CCDC18-AS1 levels are significantly higher in gastric cancer tissues than in normal tissues
High CCDC18-AS1 expression is associated with decreased patient survival
CCDC18-AS1 promotes tumor growth by inhibiting miR-214-3p

Abstract

CCDC18-AS1 is overexpressed in GC and independently predicts poor prognosis. It promotes GC progression by targeting miR-214-3p, thereby regulating key oncogenic processes.

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