Pd-Catalyzed Synthesis of Deuterated Olefins from (Hetero)Arenes and Ketones via Cross-Coupling Approach

Key Points

• The aim is to create a new method for synthesizing deuterated olefins using a cross-coupling process.
• Developed a straightforward approach for synthesis
• Utilized pd-catalysis for the reaction
• Applied to a wide range of arenes, heteroarenes, and ketones
• Focused on achieving high yields and excellent deuterium incorporation
• Demonstrated broad substrate scope for various arenes and ketones
• Achieved high yields in the synthesis of deuterated olefins
• Showed excellent incorporation of deuterium in products