Equol, a Metabolite of Daidzein, Inhibits IgE-Dependent Basophil Activation by Modulating Intracellular Signaling

Key Points

• To evaluate the effects of equol on basophil activation and its potential as an anti-allergic agent.
• In vitro experiments assessing the role of equol in IgE-dependent basophil activation.
• Analysis of intracellular signaling pathways modulated by equol.
• Equol significantly inhibits IgE-dependent basophil activation.
• The findings support the potential of equol and isoflavones as anti-allergic agents.