Sevoflurane multiple Wash In/Wash Out at the end of anesthesia to reduce agitation: a multicenter double-blind randomized controlled trial (OPERA)

Key Points

• The aim is to evaluate the effectiveness of sevoflurane wash in/wash out in reducing agitation at the end of anesthesia.
• Conducted as a multicenter double-blind randomized controlled trial.
• Participants received sevoflurane wash in/wash out at the end of anesthesia.
• Agitation levels were measured post-anesthesia.
• The intervention group experienced significantly lower agitation levels compared to the control group.
• The findings indicate that sevoflurane wash in/wash out effectively reduces post-anesthetic agitation.