This research aims to explore the preventive effects of quercetin on pulmonary fibrosis through cellular mechanisms.
Evaluated quercetin as a prophylactic agent
Examined its impact on alveolar epithelial cell priming
Assessed ferroptosis resistance levels in cells
Quercetin administration reduced the severity of pulmonary fibrosis
Enhanced ferroptosis resistance was observed in treated alveolar epithelial cells
Abstract
Our findings unveil QUE as a promising preventive agent against IPF, mediated through alveolar epithelial preconditioning to enhance ferroptosis resistance.