Copper-catalyzed 1,2-Carboesterification of 1,3-Enynes via Polarity-Matched Hydrogen Atom Transfer

Key Points

• This research aims to develop a copper-catalyzed method for the selective modification of C-H bonds using a hydrogen atom transfer strategy.
• Employed copper as a catalyst in the reaction process.
• Utilized 1,3-enynes as substrates for carboesterification.
• Focused on polarity-matched hydrogen atom transfer to achieve selectivity.
• Successful transformation of 1,3-enynes into carboesters.
• Achieved high selectivity in the C-H activation process.
• Demonstrated a novel approach to overcome challenges in synthetic chemistry.