In molecular communication via diffusion (MCvD) uplinks where multiple nano-sensors report concurrently to a fusion center (FC), the long channel memory and the near–far imbalance jointly create strong multiple access interference (MAI) coupled with residual inter-symbol/inter-chip effects. This paper studies an oversampling-enabled time-domain reception for an uplink molecular code-division multiple-access (MoCDMA) system employing bipolar molecular signalling. By exploiting intra-chip oversampling at the FC, three linear detectors following the principles of maximum ratio combining (MRC), zero-forcing (ZF), and minimum mean-square error (MMSE) are developed and further enhanced through a feedback-assisted interference subtraction (FAIS) scheme that combines single-tap ISI feedback equalization with near-to-far successive MAI subtraction. Owing to the complementary structure of bipolar molecular emissions, the signal-dependent counting noise corresponding to the two molecule types can be jointly modeled in a symmetric and information-independent manner to support unified linear detection and FAIS processing. Numerical results demonstrate that oversampling effectively improves detection reliability, while increasing the molecular emission budget alone is insufficient to mitigate near–far effects. Moreover, FAIS provides significant performance gains, particularly for far NSs.
Gao et al. (Fri,) studied this question.
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